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(4-chlorophenyl)methylcyanamide

  • Name (4-chlorophenyl)methylcyanamide
  • CAS 32111-91-4
  • Purity 99%
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Product Details

Chinese Factory Supply Wholesale (4-chlorophenyl)methylcyanamide 32111-91-4 with Cheap Price

  • Molecular Formula: C8H7 Cl N2
  • Molecular Weight: 166.61
  • Vapor Pressure: 0.00871mmHg at 25°C 
  • Boiling Point: 266.3°C at 760 mmHg 
  • PKA: -2.80±0.50(Predicted) 
  • Flash Point: 114.9°C 
  • PSA: 35.82000 
  • Density: 1.221g/cm3 
  • LogP: 2.30158 

(4-chlorophenyl)methylcyanamide(Cas 32111-91-4) Usage

General Description

(4-chlorophenyl)methylcyanamide, also known as chlorphenamide, is a chemical compound with the formula C8H8ClN3. It is an organic compound that is commonly used in the pharmaceutical industry as a carbonic anhydrase inhibitor, which means it can help to reduce the production of fluids in the body, such as cerebrospinal fluid and aqueous humor. This makes it a useful medication for treating conditions such as glaucoma, epilepsy, and edema. As a cyanamide derivative, it is also used as a building block in the synthesis of other organic and pharmaceutical compounds. However,

InChI:InChI=1/C8H7ClN2/c9-8-3-1-7(2-4-8)5-11-6-10/h1-4,11H,5H2

32111-91-4 Relevant articles

N-(4-Chlorophenyl)-N-methylcyanamide

Cunningham, Ian D.,Light, Mark E.,Hursthouse, Michael B.

, p. 1833 - 1835 (1999)

An X-ray structural analysis of the titl...

Acidity and N-methylation of N-aryl-N′-cyanoguanidines

Cunningham, Ian D.,Cox, Brian G.,Wan, Nan Chi,Povey, David C.,Smith, Gallienus W.

, p. 693 - 697 (2007/10/03)

Acid dissociation constants in water hav...

ARYLAZOMETHYLENETRIPHENYLPHOSPHORANES: A STUDY OF THE ALKYLATION REACTION

Alemagna, Andreina,Buttero, Paolo Del,Licandro, Emanuela,Papagni, Antonio

, p. 249 - 252 (2007/10/02)

The title compounds undergo alkylation r...

32111-91-4 Process route

C<sub>27</sub>H<sub>22</sub>ClN<sub>2</sub>O<sub>2</sub>P
70736-30-0

C27 H22 ClN2 O2 P

methyl iodide
74-88-4

methyl iodide

N-(4-chlorophenyl)-N-methylcyanamide
32111-91-4

N-(4-chlorophenyl)-N-methylcyanamide

C<sub>25</sub>H<sub>22</sub>ClNP<sup>(1+)</sup>*I<sup>(1-)</sup>
74378-48-6

C25 H22 ClNP(1+) *I(1-)

[(4-Chloro-phenyl)-methyl-hydrazonomethyl]-triphenyl-phosphonium; iodide

[(4-Chloro-phenyl)-methyl-hydrazonomethyl]-triphenyl-phosphonium; iodide

Conditions
Conditions Yield
With acetonitrile; at 120 ℃; for 7h;
17%
18%
43%
N-(4-chlorophenyl)-N'-cyanoguanidine

N-(4-chlorophenyl)-N'-cyanoguanidine

methyl iodide
74-88-4

methyl iodide

N-(4-chlorophenyl)-N-methylcyanamide
32111-91-4

N-(4-chlorophenyl)-N-methylcyanamide

N-(4-chlorophenyl)-N'-cyano-N-methylguanidine

N-(4-chlorophenyl)-N'-cyano-N-methylguanidine

N-(4-chlorophenyl)-N'-cyano-N,N''-dimethylguanidine

N-(4-chlorophenyl)-N'-cyano-N,N''-dimethylguanidine

N-(4-chlorophenyl)-N'-cyano-N,N'',N''-trimethylguanidine

N-(4-chlorophenyl)-N'-cyano-N,N'',N''-trimethylguanidine

Conditions
Conditions Yield
With n-butyllithium; In tetrahydrofuran; for 24h; Ambient temperature;
29%
17%
6%
28%

32111-91-4 Upstream products

  • 70736-30-0
    70736-30-0

    C27 H22 ClN2 O2 P

  • 74-88-4
    74-88-4

    methyl iodide

  • 1482-62-8
    1482-62-8

    1-(4-chlorophenyl)-3-cyanoguanidine

32111-91-4 Downstream products

  • 103037-89-4
    103037-89-4

    N -(4-chloro-phenyl)-N ,O -dimethyl-isourea

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