(4-chlorophenyl)methylcyanamide
- Name (4-chlorophenyl)methylcyanamide
- CAS 32111-91-4
- Purity 99%
Product Details
Chinese Factory Supply Wholesale (4-chlorophenyl)methylcyanamide 32111-91-4 with Cheap Price
- Molecular Formula: C8H7 Cl N2
- Molecular Weight: 166.61
- Vapor Pressure: 0.00871mmHg at 25°C
- Boiling Point: 266.3°C at 760 mmHg
- PKA: -2.80±0.50(Predicted)
- Flash Point: 114.9°C
- PSA: 35.82000
- Density: 1.221g/cm3
- LogP: 2.30158
(4-chlorophenyl)methylcyanamide(Cas 32111-91-4) Usage
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General Description |
(4-chlorophenyl)methylcyanamide, also known as chlorphenamide, is a chemical compound with the formula C8H8ClN3. It is an organic compound that is commonly used in the pharmaceutical industry as a carbonic anhydrase inhibitor, which means it can help to reduce the production of fluids in the body, such as cerebrospinal fluid and aqueous humor. This makes it a useful medication for treating conditions such as glaucoma, epilepsy, and edema. As a cyanamide derivative, it is also used as a building block in the synthesis of other organic and pharmaceutical compounds. However, |
InChI:InChI=1/C8H7ClN2/c9-8-3-1-7(2-4-8)5-11-6-10/h1-4,11H,5H2
32111-91-4 Relevant articles
N-(4-Chlorophenyl)-N-methylcyanamide
Cunningham, Ian D.,Light, Mark E.,Hursthouse, Michael B.
, p. 1833 - 1835 (1999)
An X-ray structural analysis of the titl...
Acidity and N-methylation of N-aryl-N′-cyanoguanidines
Cunningham, Ian D.,Cox, Brian G.,Wan, Nan Chi,Povey, David C.,Smith, Gallienus W.
, p. 693 - 697 (2007/10/03)
Acid dissociation constants in water hav...
ARYLAZOMETHYLENETRIPHENYLPHOSPHORANES: A STUDY OF THE ALKYLATION REACTION
Alemagna, Andreina,Buttero, Paolo Del,Licandro, Emanuela,Papagni, Antonio
, p. 249 - 252 (2007/10/02)
The title compounds undergo alkylation r...
32111-91-4 Process route
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70736-30-0
C27 H22 ClN2 O2 P
-
-
74-88-4
methyl iodide
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-
32111-91-4
N-(4-chlorophenyl)-N-methylcyanamide
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-
74378-48-6
C25 H22 ClNP(1+) *I(1-)
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[(4-Chloro-phenyl)-methyl-hydrazonomethyl]-triphenyl-phosphonium; iodide
| Conditions | Yield |
|---|---|
|
With
acetonitrile;
at 120 ℃;
for 7h;
|
17%
18% 43% |
-
-
N-(4-chlorophenyl)-N'-cyanoguanidine
-
-
74-88-4
methyl iodide
-
-
32111-91-4
N-(4-chlorophenyl)-N-methylcyanamide
-
-
N-(4-chlorophenyl)-N'-cyano-N-methylguanidine
-
-
N-(4-chlorophenyl)-N'-cyano-N,N''-dimethylguanidine
-
-
N-(4-chlorophenyl)-N'-cyano-N,N'',N''-trimethylguanidine
| Conditions | Yield |
|---|---|
|
With
n-butyllithium;
In
tetrahydrofuran;
for 24h;
Ambient temperature;
|
29%
17% 6% 28% |
32111-91-4 Upstream products
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70736-30-0
C27 H22 ClN2 O2 P
-
74-88-4
methyl iodide
-
1482-62-8
1-(4-chlorophenyl)-3-cyanoguanidine
32111-91-4 Downstream products
-
103037-89-4
N -(4-chloro-phenyl)-N ,O -dimethyl-isourea
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