4-CHLORO-2-ANISIDINE HYDROCHLORIDE
- Name 4-CHLORO-2-ANISIDINE HYDROCHLORIDE
- CAS 93-50-5
- Purity 99%
Product Details
Purity 99% Min 4-CHLORO-2-ANISIDINE HYDROCHLORIDE 93-50-5 Spot Supply with Safe Transportation
- Molecular Formula: C7H8ClNO
- Molecular Weight: 157.6
- Vapor Pressure: 0.0125mmHg at 25°C
- Melting Point: 52°C
- Refractive Index: 1.572
- Boiling Point: 260 °C at 760 mmHg
- PKA: 3.90±0.10(Predicted)
- Flash Point: 108.9 °C
- PSA： 35.25000
- Density: 1.234 g/cm3
- LogP: 2.51200
4-CHLORO-2-ANISIDINE HYDROCHLORIDE(Cas 93-50-5) Usage
InChI:InChI=1/C7H8ClNO/c1-10-7-4-5(8)2-3-6(7)9/h2-4H,9H2,1H3
93-50-5 Relevant articles
Methoxy aniline compound and synthesis method thereof
-
Paragraph 0027; 0030-0032; 0041-0042, (2021/05/19)
The invention mainly relates to a prepar...
New inha inhibitors based on expanded triclosan and di-triclosan analogues to develop a new treatment for tuberculosis
Chetty, Sarentha,Armstrong, Tom,Sharma Kharkwal, Shalu,Drewe, William C.,De Matteis, Cristina I.,Evangelopoulos, Dimitrios,Bhakta, Sanjib,Thomas, Neil R.
, (2021/05/03)
The emergence of multidrug-resistant (MD...
Nucleophilic aromatic substitution of unactivated fluoroarenes enabled by organic photoredox catalysis
Nicewicz, David A.,Pistritto, Vincent A.,Schutzbach-Horton, Megan E.
supporting information, p. 17187 - 17194 (2020/11/02)
Nucleophilic aromatic substitution (SNAr...
NEW COMPOUND HAVING FGFR INHIBITORY ACTIVITY AND PREPARATION AND APPLICATION THEREOF
-
Paragraph 0374; 0375, (2019/05/30)
The present invention relates to a new c...
93-50-5 Process route
-
-
6627-53-8
1-chloro-3-methoxy-4-nitrobenzene
-
-
93-50-5
4-chloro-o-anisidine
| Conditions | Yield |
|---|---|
|
With
ammonium formate;
platinum on activated charcoal;
In
methanol;
|
97%
|
|
With
iron; acetic acid;
In
methanol;
at 50 ℃;
Inert atmosphere;
|
94%
|
|
With
iron; ammonium chloride;
In
water;
for 0.25h;
Heating / reflux;
1-chloro-3-methoxy-4-nitrobenzene;
In
water;
Heating / reflux;
With
hydrogenchloride; sodium hydroxide; sodium hydrogencarbonate;
more than 3 stages;
Product distribution / selectivity;
|
91%
|
|
With
iron; ammonium chloride;
In
water;
for 1.5h;
Reflux;
|
86%
|
|
With
5%-palladium/activated carbon; hydrogen;
In
methanol;
for 72h;
|
76%
|
|
With
hydrogen;
nickel;
In
tetrahydrofuran;
at 20 ℃;
|
69.5%
|
|
1-chloro-3-methoxy-4-nitrobenzene;
With
water; tin(ll) chloride;
In
ethanol;
for 18h;
Heating / reflux;
With
sodium hydroxide;
In
ethanol; water;
at 20 ℃;
|
65%
|
|
1-chloro-3-methoxy-4-nitrobenzene;
With
sodium dithionite; potassium hydrogencarbonate;
In
methanol; water;
at 20 ℃;
for 2h;
With
hydrogenchloride;
In
methanol; water;
at 60 ℃;
for 2h;
pH=1;
|
64%
|
|
With
sodium dithionite; potassium hydrogencarbonate;
In
methanol; water;
at 20 ℃;
for 2h;
|
64%
|
|
With
hydrogenchloride; tin;
|
|
|
With
iron;
In
acetic acid;
|
|
|
With
ethanol; tin(ll) chloride;
Heating;
|
|
|
|
|
|
With
2 wt% Pd/C; hydrogen;
at 120 ℃;
under 7500.75 Torr;
|
-
-
90-04-0
2-methoxy-phenylamine
-
-
93-50-5
4-chloro-o-anisidine
| Conditions | Yield |
|---|---|
|
With
copper dichloride; 1-hexyl-3-methylimidazol-1-ium chloride;
at 40 ℃;
for 3h;
regioselective reaction;
|
93%
|
|
With
copper(II) choride dihydrate; lithium chloride hydrate;
In
ethanol;
for 7h;
regioselective reaction;
Reflux;
|
76%
|
93-50-5 Upstream products
-
56-23-5
tetrachloromethane
-
24251-12-5
tertiary amyl hypochlorite
-
5877-56-5
N -benzylidene-2-methoxy-aniline
-
91-23-6
2-Nitroanisole
93-50-5 Downstream products
-
35122-85-1
4-chloro-2-methoxy-N ,N -dimethyl-aniline
-
16766-30-6
4-Chloroguaiacol
-
2845-89-8
1-chloro-3-methoxy-benzene
-
755027-21-5
4-chloro-1-iodo-2-methoxybenzene
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